Starting with ESX3, virtualized Citrix Presentation Server (XenApp) workloads with a reasonable amount of users became a reality. I've virtualized many Citrix servers in production with great success. The content based page sharing mechanism really shines here. Following is a great 'Citrix on VMware' best practices article from Sven Huisman:
http://virtualfuture.info/2008/10/more-xenapp-45-on-vmware-recommendations/
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http://virtualfuture.info/2008/10/more-xenapp-45-on-vmware-recommendations/
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